University of California, Berkeley, B.A., Molecular & Cell Biology, 2010
Mechanism of resistance in non-small cell lung cancer (NSCLC) to targeted therapy.
Elton studied molecular and cell biology while at UC Berkeley. He previously worked with Dr. Tyrone Hayes on the effect of Atrazine, a commonly used herbicide, in endocrine disruption in an amphibian model (UC Berkeley, '06-'07). Then he studied gene regulation in pathogenic Salmonella at the Liu Lab (UC Berkeley, '08-'10). Since 2011, he has been at the Bivona Lab (UCSF) to study the mechanism of resistance in NSCLC to targeted therapy.
Lin L, Asthana S, Chan E, Bandyopadhyay S, Martins MM, Olivas V, Yan JJ, Pham L, Wang MM, Bollag G, Solit DB, Collisson EA, Rudin CM, Taylor BS, Bivona TG. Mapping the molecular determinants of BRAF oncogene dependence in human lung cancer. Proc Natl Acad Sci U S A. 2014 Feb 18; 111(7):E748-57. View in PubMed
Gong H, Vu GP, Bai Y, Chan E, Wu R, Yang E, Liu F, Lu S. A Salmonella small non-coding RNA facilitates bacterial invasion and intracellular replication by modulating the expression of virulence factors. PLoS Pathog. 2011 Sep; 7(9):e1002120. View in PubMed
Hayes TB, Khoury V, Narayan A, Nazir M, Park A, Brown T, Adame L, Chan E, Buchholz D, Stueve T, Gallipeau S. Atrazine induces complete feminization and chemical castration in male African clawed frogs (Xenopus laevis). Proc Natl Acad Sci U S A. 2010 Mar 9; 107(10):4612-7. View in PubMed
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